The stability of a non-homogeneous three-tier slope in rolling hill loess region in northwest Shaanxi was numerically evaluated through finite element software PLAXIS using strength reduction method. The analytical results indicated the slope stability mitigations are required. The single layer prestressed ground anchor caisson system was selected for the slope stabilization work. Under various loading combinations, the factor of safety, limits of plastic soil zone, the maximum bending moment deflections in the caisson were evaluated and the effect of anchoring location on the slope stability was also investigated. The results indicated that, when the caisson is located at the top of middle tier slope, the most appropriate position applying the ground anchor was 0.4 meters below the top of caisson.